What is it?:
Ossification is the process of bone formation, in which connective tissues, such as cartilage are turned to bone or bone-like tissue. The ossified tissue is invaginated with blood vessels. These blood vessels bring minerals like calcium and deposit it in the ossifying tissue. Bone formation is a dynamic process, with cells called osteoblasts depositing minerals, and osteoclasts removing bone.[1] This process, termed bone remodeling continues throughout life.
The clavicle is first bone in the body to ossify. Except for its medial end ,it ossifies in membrane. It ossifies from two primary centries and one secondary centre.
The two primary centres appear in the shaft between the fifth and sixth weeks of intrauterine life, and fuse about the 45th day. The secondary centre for the medial end appears during 15-17 years ,and fuses wuth the shaft during 21-22 years. Occasionally tere may be a secondary centre for the acromial end.
